Particularidades del síndrome metabólico en una subpoblación de adultos mayores / Particularities of metabolic syndrome in an elderly subpopulation

Introducción: El síndrome metabólico (SM) se define por un conjunto de alteraciones clínicas que aumentan el riesgo de enfermedad cardiovascular. Diferentes organizaciones internacionales de salud han ajustado progresivamente los criterios que definen al SM, con el consiguiente aumento del diagnóstico del mismo. Sin embargo, ninguno de los parámetros considerados se han adaptado a la edad ni se han tomado en cuenta las modificaciones antropométricas y metabólicas características del envejecimiento. Objetivo: Caracterizar al SM en una población de adultos mayores y evaluar si existen diferencias de género. Materiales y métodos: Se realizó un estudio prospectivo en pacientes que consultaron al Servicio de Endocrinología de la U. A. Dr. César Milstein. El 68,8 % fueron mujeres y la edad de la población fue 73 ± 6 años. Para el diagnóstico de SM se utilizaron los criterios del Joint Interim Statement de 2009. Recabamos información sobre antecedentes, medicación y se realizaron análisis de laboratorio. Se midió índice cintura/talla (ICT). Se calculó media ± desvío estándar (DS) y proporciones. Para establecer comparaciones entre varones y mujeres se utilizó Test de Student y test de Chi2. Resultados: En una muestra de 77 pacientes, 42,9 % cumplió con 3 componentes de SM, 33,8 % con 4 y 23,4 % con 5, con distribución similar en hombres y mujeres. Según el índice de masa corporal (IMC), 32,5 % de la población presentó sobrepeso; 35 % obesidad grado I; 22 % grado II y 9 % grado III. Al evaluar el perímetro de cintura (PC), el 98,7 % superó los puntos de corte. El índice cintura/ talla superó el valor normal en ambos sexos, siendo significativamente superior en las mujeres (p: 0,003). Conclusiones: En la población de adultos mayores que se estudió no se observó diferencia entre ambos sexos en el número de componentes diagnósticos de SM. En cuanto al perímetro de cintura, el valor fue similar en ambos sexos, lo que podría llevar a revisar el valor de corte del mismo en este grupo etario. El ICT estuvo aumentado en toda la población y por ser un subrogante de riesgo cardiovascular, sería otro parámetro a tener en cuenta al momento del diagnóstico de SM. Rev Argent Endocrinol Metab 51:130-135, 2014 Los autores no poseen conflictos de interés.

Introduction: The metabolic syndrome (MS) denotes an association of abnormalities that increase the risk of cardiovascular disease. With the intention of decreasing this risk, international organizations have dropped the normal range for various parameters, with a consequent increase in the diagnosis of MS. Although the changes related to age are well documented, none of these parameters has been age-adapted. Aims: to characterize MS in the elderly population and to establish possible gender differences. Materials and methods: We performed a prospective study in patients who presented at the Department of Endocrinology of the Healthcare Unit Dr. Cesar Milstein. Of the total population, 68.8 % were women and the average age was 73 ± 6 years. For the diagnosis of MS, we used the 2009 Joint Interim Statement diagnostic criteria. Information was collected on previous history and medication, and laboratory analyses were performed. The waist / height ratio was also measured. Mean ± standard deviation (SD) and proportions were calculated. For comparisons between men and women, the Student test and Chi-squared test were used. Results: Of the total population, 42.9 % fulfilled 3 criteria for MS, 33.8 % fulfilled 4 criteria and 23.4 % fulfilled 5, with similar distribution in men and women. According to body mass index (BMI), 32.5 % of the population had overweight, 35 % were grade I obese, 22 % were grade II and 9 % were grade III. As regards waist circumference, 98.7 % of the total population exceeded the established cutoffs. The waist/ height ratio exceeded normal values in both genders, being significantly higher in women (p = 0.003). Conclusions: In the elderly, there are no gender differences in the number of components of MS. As for waist circumference, values were similar in both men and women. This finding could lead to redefine the cutoff value in aged woman. The waist / height ratio, a surrogate marker of cardiovascular disease, was ...

Desempenho de vacas Girolando mantidas em pastejo de Tifton 85 irrigado ou sequeiro / Performance of crossbred Holstein x Zebu cows rotationally grazing in Tifton 85 pasture irrigated or rainfed

Objetivou-se com este trabalho avaliar a taxa de lotação e a produção de leite de vacas mestiças Holandês x Zebu em pastagens de Tifton 85 irrigadas e em sequeiro, em Uberaba-MG. Os dados foram analisados em um delineamento de blocos inteiramente ao acaso, com três repetições por tratamento, num esquema fatorial 2x10 (dois tratamentos e 10 épocas). Foi utilizado um lote de 11 vacas em lactação por tratamento para avaliação do desempenho animal. As médias foram comparadas por meio do teste de Scott-Knott ao nível de 5% de probabilidade (P<0,05). A pastagem foi manejada em sistema de pastejo rotacionado com três e cinco dias de ocupação e 21 e 35 dias de descanso no período das águas e da seca, respectivamente. A taxa de lotação média do sistema irrigado, no período avaliado, foi de 4,6 UA.ha-1, valor superior (P<0,05) à taxa média de 2,2 UA.ha-1 observada para o sistema de sequeiro. Não houve diferenças nas produções diárias de leite das vacas (P<0,05). A produção de leite média obtida no sistema irrigado foi de 51,7 litros. ha-1.dia-1. A irrigação possibilitou uma considerável intensificação do sistema, na medida em que proporcionou uma taxa de lotação bastante superior ao sistema de sequeiro.

The aim of this study was to determine the stocking rates and milk production of crossbred Holstein x Zebu cows managed under irrigated or rainfed Tifton 85 pastures in Uberaba- MG. The statistical design adopted was completely randomized blocks with three repetitions per treatment, in a 2 x 10 factorial arrangement (2 treatments and 10 seasons). The average was compared using the Scott-Knott test with 5% probability (P<0.05). To evaluate animal performance, 11 lactating cows per treatment were used. The pasture was managed in a rotational grazing system with 21 and 35 days of grazing interval and 3 and 5 days of grazing in each paddock, in the rainy and dry seasons respectively. The stocking rate of the irrigated system was 4.6 UA.ha-1 and was superior (p<0.05) to the stocking rate of the rainfed system that was 2.2 UA.ha-1. There were no differences among the systems (p>0.05) for the average daily milk yield of the cows. In the irrigated system the average milk yield was 51.7 liters.ha-1.dia-1. With irrigation, a considerable intensification of the system was possible because it provided a superior stocking rate capacity compared to the rainfed system.

Plasma von Willebrand factor as a predictor of survival in pulmonary arterial hypertension associated with congenital heart disease

Biomarkers have been identified for pulmonary arterial hypertension, but are less well defined for specific etiologies such as congenital heart disease-associated pulmonary arterial hypertension (CHDPAH). We measured plasma levels of eight microvascular dysfunction markers in CHDPAH, and tested for associations with survival. A cohort of 46 inoperable CHDPAH patients (age 15.0 to 60.2 years, median 33.5 years, female:male 29:17) was prospectively followed for 0.7 to 4.0 years (median 3.6 years). Plasma levels of von Willebrand factor antigen (VWF:Ag), tissue plasminogen activator (t-PA) and its inhibitor (PAI-1), P-selectin, reactive C-protein, tumor necrosis factor alpha, and interleukin-6 and -10 were measured at baseline, and at 30, 90, and 180 days in all subjects. Levels of six of the eight proteins were significantly increased in patients versus controls (13 to 106 percent increase, P < 0.003). Interleukin-10 level was 2.06 times normal (P = 0.0003; Th2 cytokine response). Increased levels of four proteins (t-PA, PAI-1, P-selectin, and interleukin-6) correlated with disease severity indices (P < 0.05). Seven patients died during follow-up. An average VWF:Ag (mean of four determinations) above the level corresponding to the 95th percentile of controls (139 U/dL) was independently associated with a high risk of death (hazard ratio = 6.56, 95 percentCI = 1.46 to 29.4, P = 0.014). Thus, in CHDPAH, microvascular dysfunction appears to involve Th2 inflammatory response. Of the biomarkers studied, plasma vWF:Ag was independently associated with survival.

Rosuvastatin and vascular dysfunction markers in pulmonary arterial hypertension: a placebo-controlled study

We investigated whether chronic rosuvastatin administration could improve the abnormalities of the circulating levels of vascular dysfunction markers in pulmonary arterial hypertension (PAH). Sixty patients, aged 13 to 60 years, with idiopathic (N = 14) or congenital heart disease-associated PAH (N = 46) were equally but randomly assigned to rosuvastatin treatment (10 mg a day, orally) or placebo for 6 months in a blind fashion. Plasma levels of P-selectin, tissue-plasminogen activator and its inhibitor as well as von Willebrand factor antigen were measured by enzyme-linked immunoassay before and after 1, 3, and 6 months of treatment. Baseline levels of biomarkers were elevated (68, 16, 45 and 46 percent increase relative to controls, for P-selectin, von Willebrand factor antigen, tissue-plasminogen activator and its inhibitor, respectively; P < 0.001). P-selectin values at baseline, 1, 3, and 6 months were 39.9 ± 18.5, 37.6 ± 14.6, 34.8 ± 14.6, and 35.4 ± 13.9 ng/mL, respectively, for the rosuvastatin group and 45.7 ± 26.8, 48.0 ± 26.9, 48.1 ± 25.7, and 45.7 ± 25.6 ng/mL for the placebo group. The P-selectin level was lower in the rosuvastatin group compared with placebo throughout treatment (P = 0.037, general linear model). A trend was observed towards a decrease in tissue-plasminogen activator in the statin group (16 percent reduction, P = 0.094), with no significant changes in the other markers. Since P-selectin is crucial in inflammation and thrombosis, its reduction by rosuvastatin is potentially relevant in the pathophysiological scenario of PAH.

Cost-effective analysis of different algorithms for the diagnosis of hepatitis C virus infection

We compared the cost-benefit of two algorithms, recently proposed by the Centers for Disease Control and Prevention, USA, with the conventional one, the most appropriate for the diagnosis of hepatitis C virus (HCV) infection in the Brazilian population. Serum samples were obtained from 517 ELISA-positive or -inconclusive blood donors who had returned to Fundação Pró-Sangue/Hemocentro de São Paulo to confirm previous results. Algorithm A was based on signal-to-cut-off (s/co) ratio of ELISA anti-HCV samples that show s/co ratio ≥95 percent concordance with immunoblot (IB) positivity. For algorithm B, reflex nucleic acid amplification testing by PCR was required for ELISA-positive or -inconclusive samples and IB for PCR-negative samples. For algorithm C, all positive or inconclusive ELISA samples were submitted to IB. We observed a similar rate of positive results with the three algorithms: 287, 287, and 285 for A, B, and C, respectively, and 283 were concordant with one another. Indeterminate results from algorithms A and C were elucidated by PCR (expanded algorithm) which detected two more positive samples. The estimated cost of algorithms A and B was US$21,299.39 and US$32,397.40, respectively, which were 43.5 and 14.0 percent more economic than C (US$37,673.79). The cost can vary according to the technique used. We conclude that both algorithms A and B are suitable for diagnosing HCV infection in the Brazilian population. Furthermore, algorithm A is the more practical and economical one since it requires supplemental tests for only 54 percent of the samples. Algorithm B provides early information about the presence of viremia.

Efecto de la vitamina E en el proceso de hemostasia de individuos sanos / Effect of vitamin E in haemostasis of healthy individuals

La vitamina E (VE) es una vitamina liposoluble que actúa como antioxidante y ha sido asociada a tiempos prolongados de sangramiento en individuos sanos. El objetivo del siguiente trabajo fue evaluar el efecto de la VE en el proceso de coagulación de personas sanas. Fueron incluidos en el estudio 211 individuos sanos sin historia de enfermedades que comprometieran la hemostasia y separados en dos grupos dependiendo de la ingesta o no de VE. Los datos epidemiológicos de cada paciente así como el tiempo de protrombina (PT) y el tiempo parcial de tromboplastina (PTT) fueron recolectados. Todos los datos fueron analizados mediante el programa estadístico SPSS versión 13.0 y las medias comparadas usando la prueba estadística t de student. 114 individuos consumian al menos 400mgrs diarios de VE por un lapso no menor de 3 meses (75 mujeres y 39 hombres, edad promedio de 53.82+1.7 años) y 97 individuos que no consumian VE (55 mujeres y 42 hombres, edad media de 54.29+1.9 años) fueron incluidos como grupo control. El grupo que consumía VE mostró valores de PT estadísticamente mayores que los controles (p=0.001) (14.3+0.23seg y 13.2+0.23seg respectivamente). Así mismo, los valores de PTT del grupo VE estuvieron estadísticamente por encima de los pacientes control (p<0.0001) (31.19+0.33seg y 28.69+0.18seg respectivamente). El presente estudio sugiere que el consumo contínuo de VE podría alterar los valores de PT y PTT en individuos sanos y por tal razón modificar el proceso de coagulación normal

Vitamin E (VE) is a fat-soluble vitamin that acts as an antioxidant and it has been associated to prolonged bleeding in healthy individuals. The aim of this study was to evaluate the effect of VE in haemostasis. 211 healthy individuals were included and separated into groups depending on the VE ingest. Epidemiological data, prothrombin time (PT) and activated partial thromboplastin time (PTT) were collected. Data was analysed using SPSS 13.0 and means compared by t student test. 114 individuals consuming VE regularly (75 women and 39 men, mean age 53.82+1.7 years) and 97 controls (55 women and 42 men, mean age 54.29+1.9 years) were evaluated. VE group showed PT values significantly higher (p=0.001) than controls (14.3+0.23sec and 13.2+0.23sec respectively), as well as statically augmented PTT times (p<0.0001) (31.19+0.33sec 28.69+0.18sec respectively). VE may alter PT and PTT values in healthy people and therefore modifies haemostasis

One-year follow-up of the effects of sildenafil on pulmonary arterial hypertension and veno-occlusive disease

We hypothesized that chronic oral administration of the phosphodiesterase-5 inhibitor sildenafil could improve the exercise capacity and pulmonary hemodynamics in patients with pulmonary arterial hypertension (PAH) on the basis of previous short-term studies. We tested this hypothesis in 14 subjects with PAH, including seven patients with the idiopathic form and seven patients with atrial septal defects, but no other congenital heart abnormalities. Patients were subjected to a 6-min walk test and dyspnea was graded according to the Borg scale. Pulmonary flow and pressures were measured by Doppler echocardiography. Patients were given sildenafil, 75 mg orally three times a day, and followed up for 1 year. Sildenafil therapy resulted in the following changes: increase in the 6-min walk distance from a median value of 387 m (range 0 to 484 m) to 462 m (range 408 to 588 m; P < 0.01), improvement of the Borg dyspnea score from 4.0 (median value) to 3.0 (P < 0.01), and increased pulmonary flow (velocity-time integral) from a median value of 0.12 (range 0.08 to 0.25) to 0.23 (range 0.11 to 0.40; P < 0.01) with no changes in pulmonary pressures. In one patient with pulmonary veno-occlusive disease diagnosed by a lung biopsy, sildenafil had a better effect on the pulmonary wedge pressure than inhaled nitric oxide (15 and 29 mmHg, respectively, acute test). He walked 112 m at baseline and 408 m at one year. One patient died at 11 months of treatment. No other relevant events occurred. Thus, chronic administration of sildenafil improves the physical capacity of PAH patients and may be beneficial in selected cases of veno-occlusive disease.

Accidentes biológicos por exposición percutánea y contacto cutáneo-mucoso en el personal de enfermería del Instituto Autónomo Hospital Universitario de Los Andes, Mérida, Venezuela, 2003 / Biological accidents due to percutaneous exposure and cutaneous-mucous contact among nursing personnel in the Autonomous Institute of Los Andes University Hospital, Mérida, Venezuela, 2003

Objetivo: determinar las principales características de los accidentes biológicos por exposición percutánea y contacto cutáneo-mucoso en el personal de enfermería del Instituto Autónomo Hospital Universitario de Los Andes (IAHULA) de Mérida, Venezuela, en el año 2003. Materiales y métodos: la investigación de tipo descriptivo y diseño transversal estimó un tamaño muestral de 161 trabajadores de la enfermería (23,9 por ciento del total de este personal). Resultados: se encontró una alta frecuencia de los accidentes percutáneos (83,2 por ciento), con una tasa de prevalencia de 129,8 accidentes por cada 100 trabajadores y un índice de incidencia de 1,6 accidentes por trabajador. La frecuencia de los accidentes por contacto cutáneo-mucoso también resultó elevada (80,1 por ciento), con una tasa de 134,2 y un índice de incidencia de 1,7. El área de mayor accidentalidad fue la unidad de cuidados intensivos. Los licenciados con edades entre 30 y 39 años y más de 10 años de actividad laboral fueron los más afectados. Las agujas huecas de pequeño y gran calibre conectadas a jeringas desechables fueron el material más implicado en la producción del accidente (73,7 por ciento) y la actividad involucrada con mayor frecuencia resultó ser la administración de medicamentos (39,3 por ciento). Por el reencapsulado de agujas se produjo el 27,8 por ciento de los accidentes percutáneos. La desinfección de la herida, su lavado y el inducir al sangrado fue la conducta más frecuente. La profilaxis se realizó con vacuna antitetánica y antihepatitis B. Conclusión: los accidentes biológicos constituyen una verdadera problemática en la institución estudiada, lo que hace imperativo su tratamiento preventivo y el control de riesgos

Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach

How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22 percent) were positive and 32 (78 percent) were negative for HTLV-1/2. The demographic analysis indicated a trend towards a predominance of males among the seroindeterminate individuals and females in the seropositive ones. The seroindeterminate individuals were younger than the seropositive ones. We did not find any association of these conditions with syphilis, Chagas disease or HIV or hepatitis, and with risk factors such as breast-feeding, blood transfusion, STD (syphilis) and IDU

Peritoneal catheter extrusion through the scrotal sac: case report

Peritoneal catheter extrusion throught the scrotal sac: the extrusion of a peritoneal catheter throught the scrotal bolsa following ventriculoperitoneal shunt is unconmmon. The authors report a case of peritoneal catheter extrusion through the scrotal sac a 5-month-old child, with excellent outcome.

Gastrointestinal parasites and prey items from a mass stranding of false killer whales, Pseudorca crassidens, in Rio Grande do Sul, Southern Brazil

The gastrointestinal tract of 14 false killer whales, 6 males and 8 females, stranded in June 1995 in southern Brazil, with total standard lengths from 338 to 507 cm, were analysed for endoparasites and food items. A pregnant female had a male foetus of 77.5 cm. Parasites were found in all 14 false killer whales. The nematode Anisakis simplex (Rudolphi, 1809) was found in the stomach of 57 percent of the animals and the acanthocephalan Bolbosoma capitatum (Linstow, 1889) Porta, 1908 was present in the intestine of all specimens and showed densities up to 600 m-1. An unidentified cestode (Tethrabothridae) was found also in the intestines of 14 percent of the individuals. The high infections of B. capitatum and A. simplex were not directly related with the cause of death. In the stomachs of four females, beaks of at least eight specimens of the oceanic and epipelagic species Ommastrephes bartramii (Lesueur, 1821) were found, with mantle lengths ranging from 189.8 to 360.9 mm. The distribution of O. bartramii in the coast of Rio Grande do Sul is consistent with false killer whales feeding in continental shelf waters

Eficacia terapéutica del Nimesulide en el tratamiento de la dorso lumbalgia de origen traumático / Therapeutic effectiveness of the nimesulide in the treatment of the low back pain of traumatic origin

Se realizó un estudio abierto, no controlado, multicéntrico, realizado con intención de tratar, en 60 pacientes con dorsolumbalgia mecánica, en el cual evaluó la efectividad y seguridad de nimesulide 100 mg dos veces al día, administrado durante 15 días. El tratamiento produjo un alivio significativo en los escores de dolor entre el día de inicio del tratamiento y los 5 días, con un alivio adicional importante entre los días 5 y 10, sin alivios adicionales para el día 15. El tiempo medio para la desaparición total del dolor fue de 8,5 días. La limitación funcional fue evaluada el día 0 y el día 15, obteniéndose una mejoría significativa desde el punto de vista estadístico. Se reportaron efectos adversos en 4 de los pacientes, de los cuales sólo uno ameritó la suspensión del tratamiento

DNA fingerprinting of mycobacterium tuberculis from patients with and without AIDS in Rio de Janeiro

Isolates of Mycobacterium tuberculosis derived from patients with AIDS from a single hospital in Rio de Janeiro were typed using a standardized RFLP technique detecting IS6110 polymorphism. Nineteen isolates were obtained from 15 different patients. Eleven distinct IS6110 patterns were found, with 4 banding patterns shared by 2 patients. The clustering value of 53 percent was much higher in comparison with clustering of M. tuberculosis strains from TB patients without clinical signs for HIV infection from randomly selected health centers. We present these results as preliminary data on M. tuberculosis strain polymorphism in Brazil and on the higher risk for recent transmission amongst patients with AIDS.

Fascitis necrotizante / Necrotizing fascitis

La fascitis necrotizante es una infección que progresa rápidamente necrosando los tejidos, afectando al celular subcutáneo y fascia subyacente, acompañada de toxicidad sistémica. El reconocimiento tardío de esta infección provoca una alta mortalidad. Se presenta la experiencia de nuestro hospital en el tratamiento de 27 pacientes ingresados entre enero 1994 a junio 1996. La localización más frecuente fue perineal en 17 pacientes, seguida por extremidades inferiores en 8. La mitad de los pacientes tenían patología médica asociada, siendo un tercio del total portadores de diabetes mellitus. Todos ellos fueron sometidos a cirugías resectivas. Veinticinco de ellos requirieron 26 más cirugías llegando hasta 5 intervenciones en dos pacientes. La etiología bacteriana en la mitad de los casos fue polimicrobiana. En 5 pacientes se cultivo estreptococo beta hemolítico grupo A, aislado o asociado a otros gérmenes. La letalidad en esta serie corresponde al 29,6 por ciento, y todos fallecieron debido a falla multiorgánica

Colera em Mocambique no seculo XIX : II. tratamento utilizado na epoca

Este e o segundo artigo de uma serie de tres; relativa a epidemia de colera que assolou a Ilha de Mocambique; de Fevereiro a Marco no ano de 1859. No presente artigo apresentam-se e analisam-se aspectos relacionados com o diagnostico e tipo de tratamento utilizado; os recursos humanos e materiais existentes e o estabelecimento de um sistema de organizacio sanitaria onde participaram para alem do pessoal de saude; elementos da comunidade para apoio ao tratamento domiciliar dos casos. O aspecto mais importante; tendo em conta outras epidemias ocorridas durante o mesmo periodo na Europa e America; foi a participacio activa da populacio em relacio as medidas de tratamento preconizado palas autoridades de saude

Prevalência de anticorpos anti-HTLVI/II em doadores de sangue da Fundaçäo Pró-Sangue Hemocentro de Säo Paulo / Prevalence of anti-HTLVI/II antibodies in blood donors of Fundaçäo Pró-Sangue Hemocentro de Säo Paulo

O teste ELISA ant-HTLVI/II foi introduzido na triagem sorlógica de doadores de sangue na Fundaçäo Pró-sangue Hemocentro de Säo Paulo (FPS/HSP) em julho de 1991. NO período compreendido entre julho de 1991 e julho de 1994 foram submetidos à triagem serológica 597.727 doadores. Destes, 7682 foram recusados por terem apresentado reatividade no teste ELISA anti-HTLVI/II. A positividade observada, para o referido teste, foi diminuindo com o correr do tempo: 2,12 por cento em 1991; 1,6 por cento em 1992; 0,8 por cento em 1993 e 1,0 por cento em 1994, sendo esse fato atribuido a melhora da especialidade e reprodutividade dos kits comerciais. Foi utilizado o teste suplementar de Western Blot para confirmar os resultados dos testes ELISA. Em 249 amostras de soros de doadores, com resultado repetidamente positivo (RRP) no teste ELISA (hemobio), o poder confirmatório do Western Blot (Cambridge Biotech) foi de 24.9 por cento (IC/90 por cento: 20,4 por cento-29,39 por cento). Baseados nesses dados, considera-se uma expectativa de prevalência de indivíduos infectados pelo HTLVI/II, na populaçäo de doadores de sangue da FPS/HSP de 0,142 por cento (IC/90 por cento; 0,116 por cento-0,167 por cento). Em 437 amostras de soro de doadores que retornaram ao Banco de Sangue, para confirmar o resultado inicial e apresentaram RRP no teste ELISA, o poder confirmatório do Western Blot foi de 34,55 por cento (IC/90 por cento: 30,82 por cento-38,28 por cento)...